SAM-e promotes joint strength, liver detoxification, mood, and brain function. Jarrow Formulas SAM-e provides a full 200 mg SAM-e (net yield)from 400 mg of SAM-e tosylate disulfate. SAM-e 200 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

SAM-e 200 contains the highest active level available of the active S,S form of SAM-e. Found in all living cells, SAM-e is a metabolite of methionine (an essential amino acid). SAM-e is a chiral molecule and consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive. Jarrow Formulas SAM-e is made naturally by microbiological fermentation and then specially processed without solvents to preserve 68-80% (S,S) SAM-e.

SAM-e has been clinically shown to support joint strength, brain metabolism, and the liver.

Joint Strength
SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroitin sulfates, are sulfated by SAM-e metabolites.

Brain Metabolism
SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-DOPA, dopamine and related hormones, serotonin, epinephrine and phosphatidylcholine (a component of lecithin).

Liver
SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathione-dependent enzymes (glutathione peroxidase and glutathione-S-transferase), which are substances important for liver function.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested Use

Take 1 tablet 1 or 2 times per day on an empty stomach or as directed by your qualified healthcare professional.

WARNING: Individuals using prescribed medications such as antidepressants, including Selective Serotonin Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors should consult a physician before using. Individuals with Parkinson’s disease, bi-polar disorder or manic depression should not use SAM-e. Do not use if pregnant or nursing. Do not exceed recommended dose. May cause gastrointestinal upset in some persons. If you experience discomfort, discontinue use.

Supplement Facts

Serving Size: 1 tablet
Servings per Container: 60

Amount per Serving, %Daily Value
S-Adenosyl Methionine 200 mg †
   (from 400 mg of SAM-e tosylate disulfate)
† Daily Value not established.

Other Ingredients Cellulose, mannitol, glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide,sodium starch glycolate, enteric coating (methacrylate copolymers), magnesium silicate, titanium dioxide, triethyl citrate, and riboflavin.

No wheat, no gluten, no soybeans, no dairy,no egg, no fish/shellfish, no peanuts/tree nuts. Suitable for vegetarians/vegans.

Information Source: Jarrow Formulas  Emerson product code: J00161